Studije na životinjama pokazale su manju stopu trudnoća i smanjeno preživljavanje kod mladunčadi pacova pri primeni visokih doza. Nema podataka koji se odnose na ljude.Oni mogu biti udruženi sa drugim neželjenim reakcijama uključujući promene raspoloženja, anksioznost ili poremećaje spavanja i uznemirenost. S obzirom naHronična upotreba
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